首页> 外国专利> A BILAYER PHARMACEUTICAL TABLET COMPRISING A FIRST TELMISARTAN-CONTAINING TABLET LAYER AND A SECOND DISINTERGRATING TABLET LAYER CONTAINING A DIURETIC AND THE PREPARATION THEREOF

A BILAYER PHARMACEUTICAL TABLET COMPRISING A FIRST TELMISARTAN-CONTAINING TABLET LAYER AND A SECOND DISINTERGRATING TABLET LAYER CONTAINING A DIURETIC AND THE PREPARATION THEREOF

机译:包含第一含替米沙坦的片剂层和包含利尿剂的第二可分解的片剂双层的双层药物片剂及其制备方法

摘要

The invention relates to new solid pharmaceutical compositions comprising the angiotensin II receptor antagonist telmisartan, a basic agent, a surfactant or emulsifier and a water-soluble diluent, e.g. in form of granules or in form of a powder, as well as solid oral formulations ready for use/ingestion, e.g. capsule and tablet formulations made from said pharmaceutical compositions, and methods for producing said compositions and formulations making use of a fluid-bed granulation process or of a spray-drying process.
机译:本发明涉及新的固体药物组合物,该组合物包含血管紧张素Ⅱ受体拮抗剂替米沙坦,碱性剂,表面活性剂或乳化剂和水溶性稀释剂,例如盐酸。以颗粒形式或粉末形式,以及准备使用/摄取的固体口服制剂,例如由所述药物组合物制成的胶囊和片剂制剂,以及利用流化床制粒法或喷雾干燥法制备所述组合物和制剂的方法。

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