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Use of dha, epa or dha-derived epa for treating a pathology associated with cellular oxidative damage

机译：dha，epa或dha衍生的epa在治疗与细胞氧化损伤相关的病理学中的用途

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摘要

The present invention relates to docosahexaenoic acid or eicosapentaenoic acid or DHA-derived EPA characterized in that said docosahexaenoic acid or eicosapentaenoic acid or DHA-derived EPA is incorporated into a monoglyceride, diglyceride, triglyceride, or phospholipid, and in that said docosahexaenoic acid or eicosapentaenoic acid or DHA-derived EPA is found in a percentage by weight between 20 and 100% in relation to the total fatty acids, for use in the treatment of a pathology associated with cellular oxidative damage.

机译：本发明涉及二十二碳六烯酸或二十碳五烯酸或DHA衍生的EPA ，其特征在于，所述二十二碳六烯酸或二十碳五烯酸或DHA衍生的EPA被掺入甘油单酸酯，甘油二酸酯，甘油三酸酯或磷脂中，和其特征在于，发现所述二十二碳六烯酸或二十碳五烯酸或DHA衍生的EPA相对于总脂肪酸的重量百分比为20至100％，用于治疗与细胞氧化损伤相关的病理。 展开▼

著录项

公开/公告号EP2510927A2

专利类型

公开/公告日2012-10-17

原文格式PDF

申请/专利权人 BRUDY TECHNOLOGY S.L.;
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申请/专利号EP20110189179

发明设计人 DOMINGO PEDROL JOAN CARLES;VILLEGAS GARCIA JOSE ANTONIO;
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申请日2006-12-20

分类号A61K31/202;A23L1/30;A61K47/14;A61K47/12;A61K47/24;A61P25/16;A61P25/28;A61P27/12;A61P9/10;A61P9/02;

国家 EP

入库时间 2022-08-21 17:11:29

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1. DHA、EPA或DHA衍生的EPA用于治疗细胞氧化损伤相关疾病的用途 [P] . 中国专利： CN103263406B . 2015.03.25

2. DHA、EPA或DHA衍生的EPA用于治疗细胞氧化损伤相关疾病的用途 [P] . 中国专利： CN101346138B . 2013.03.13

3. Use of DHA, EPA or DHA-derived EPA for treating a pathology associated with cellular oxidative damage [P] . 美国专利： US10493008B2 . 2019-12-03

机译：使用DHA，EPA或DHA衍生的EPA治疗与细胞氧化损伤相关的病理

4. USE OF DHA, EPA OR DHA-DERIVED EPA FOR TREATING A PATHOLOGY ASSOCIATED WITH CELLULAR OXIDATIVE DAMAGE [P] . 欧洲知识产权局专利： EP3263101A1 . 2018-01-03

机译：使用DHA，EPA或DHA衍生的EPA治疗与细胞氧化损伤有关的病理

5. Use of DHA, EPA or DHA-derived EPA for treating a pathology associated with cellular oxidative damage [P] . NO341240B1 . 2017-09-25

机译：使用DHA，EPA或DHA衍生的EPA治疗与细胞氧化损伤相关的病理

1. Determination of Partial Molar Volumes of EPA and DHA Ethyl Esters in Supercritical Carbon Dioxide [J] . 中国化学快报（英文版） . 2002,第001期

2. Deptermination of Partial Molar Volumes of EPA and DHA Ethyl Esters in Supercritical Carbon Dioxide [J] . MeiHUANG, XianDaWANG, 等中国化学快报：英文版 . 2002,第001期

3. A Comparative Study About the Neuroprotective Effects of EPA-Enriched Phosphoethanolamine Plasmalogen and Phosphatidylethanolamine Against Oxidative Damage in Primary Hippocampal Neurons [J] . ZHU Yunfang, ZHANG Tiantian, DING Lin, 中国海洋大学学报（英文版） . 2021,第005期

4. Scientific Opinion on the substantiation of health claims related to eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and maintenance of normal cardiac function (ID 504, 506, 516, 527, 538, 703, 1128, 1317, 1324, 1325), maintenance of normal blood glucose concentrations (ID 566), maintenance of normal blood pressure (ID 506, 516, 703, 1317, 1324), maintenance of normal blood HDL‐cholesterol concentrations (ID 506), maintenance of normal (fasting) blood concentrations of triglycerides (ID 506, 527, 538, 1317, 1324, 1325), maintenance of normal blood LDL‐cholesterol concentrations (ID 527, 538, 1317, 1325, 4689), protection of the skin from photo‐oxidative (UV‐induced) damage (ID 530), improved absorption of EPA and DHA (ID 522, 523), contribution to the normal function of the immune system by decreasing the levels of eicosanoids, arachidonic acid‐derived mediators and pro‐inflammatory cytokines (ID 520, 2914), and “immunomodulating agent” (4690) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [J] . EFSA Journal . 2010,第10期

5. EPA- and DHA-derived resolvins' actions in inflammatory bowel disease [J] . Schwanke Raquel Cristina, Marcon Rodrigo, Bento Allisson Freire, European Journal of Pharmacology: An International Journal . 2016,第Null期

6. First total synthesis of labeled EPA and DHA-derived A-type cyclopentenone isoprostanoids: [D_2]-15-A_(3t)-IsoP and [D_2]-17-A_(4t)-NeuroP [J] . Alessio Porta, Enrico Brunoldi, Giuseppe Zanoni, Tetrahedron . 2014,第7期

7. Concentration of DHA and EPA from marine fish oil by urea complexation [C] . Chunzhi Zhang, Ming Chen, Zhiguo Mao, International conference on chemical engineering, metallurgical engineering and metallic materials . 2012

8. Synthesis and identification of EPA-derived isoprostanes. Discovery of DHA-derived neurofurans in vivo [D] . Chang, Chih-Tsung 2008

9. Switching from EPA + DHA (Omega-3-acid Ethyl Esters) to High-Purity EPA (Icosapent Ethyl) in a Statin-Treated Patient with Persistent Dyslipidemia and High Cardiovascular Risk: A Case Study [O] . James R. Crandell 2016

10. EPA or DHA enhanced oxidative stress and aging protein expression in brain of d-galactose treated mice [O] . Yuan-Man Hsu, Mei-Chin Yin 2016

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2. EVIDENCE FOR AMELIORATION OF CELLULAR DAMAGE IN ISCHEMIC RAT BRAIN BY RADIX SALVIAE MILTIORRHIZAE TREATMENT——IMMUNOCYTOCHEMISTRY AND HISTOPATHOLOGY STUDIES [J] . 匡培根 ,吴卫平 ,朱克 . 中医杂志：英文版 . 1993,第1期

3. 免疫营养素(GLN,EPA,DHA)及化疗药物对胃癌细胞系生长干预的实验研究 [C] . 于健春 ,张宏 ,彭维朝 . 中华医学会第十一届全国营养支持学术会议 . 2008

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