Copper-Capped Nanoparticle Array Biochip Based on LSPR Optical Properties and Use Thereof

摘要

The invention localized surface plasmon resonance (LSPR) copper deposition type nano that particles of the array of the bio-chip, and more specifically, the metal thin film layer, arranged on the metal thin film layer at an interval nanoparticles constant formed on a substrate that is based on the optical properties that the nanoparticle array layer, which comprises a copper thin-film layer formed on the copper layer deposited nanoparticle array type nanoparticle array bio-chip; The copper deposition-type nano-particles have one or more bio-receptor is immobilized on the surface of the bio-chip array, target biomaterials or unlabeled candidate target optical biosensor in the interaction with the bio-material can be detected and / or quantified; And to its use. ; Copper deposition type nanoparticle array biochip according to the invention are conventional gold or silver nanoparticles, as well as having the advantage of LSPR based optical bio-chip with an array of bio-chip, the copper deposition type nanoparticle source to the array bio-chip, a detector, a spectrophotometer and by combining the LSPR optical characterization system that includes a computer, it can be applied to the unlabeled optical biosensor in the interaction of the various bio-materials can be detected with high sensitivity. ; Localized Surface Plasmon Resonance (LSPR) optical properties, nano-particles, copper, copper metal evaporated nanoparticle array biochip, unlabeled optical biosensor