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ANTI-ASCT2(SYSTEM ASC AMINO ACID TRANSPORTER TYPE 2) ANTIBODY

机译:ANTI-ASCT2(系统ASC氨基酸转运蛋白2型)抗体

摘要

An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (ASCT2) or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of system ASC amino acid transporter 2 (ASCT2) and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.
机译:本发明的目的是提供一种单克隆抗体,其可用于治疗或诊断与系统ASC氨基酸转运蛋白2(ASCT2)有关的疾病或使用该抗体的方法。本发明提供一种单克隆抗体,其特异性识别系统ASC氨基酸转运蛋白2(ASCT2)的细胞外区域的天然三维结构,并结合至细胞外区域,或其抗体片段。产生抗体的杂交瘤;编码抗体的DNA;含有DNA的载体;通过引入载体可获得的转化体;使用杂交瘤或转化体生产抗体或其抗体片段的方法;使用该抗体或其抗体片段的治疗剂和使用该抗体或其抗体片段的诊断剂。

著录项

  • 公开/公告号KR20120115511A

    专利类型

  • 公开/公告日2012-10-18

    原文格式PDF

  • 申请/专利权人 KYOWA HAKKO KIRIN CO. LTD.;

    申请/专利号KR20127017400

  • 发明设计人 KUBOTA TSUGUO;

    申请日2011-01-14

  • 分类号C07K16/28;C12N15/13;A61K39/395;A61P35;

  • 国家 KR

  • 入库时间 2022-08-21 17:08:54

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