METHOD FOR IMPROVEMENT OF DENDRITIC CELL MIGRATION AND OF CTL CYTOTOXICITY GENERATED WITH DENDRITIC CELLS

摘要

PURPOSE: A method for enhancing cytotoxicity of cytotoxic T cells is provided to enhance mobility of dendritic cells to a second lymph organ and to induce maturation of novel dendritic cells. CONSTITUTION: A method for enhancing cytotoxicity of cytotoxic T cells comrises: a step of differentiating monocytes isolated from blood into immature dendritic cells; a step of treating antiviral cytokines, TLR activator, or mixture thereof to the immature dendritic cells to culture the immature dendritic cells; a step of treating a composition for enhancing mobility of dendritic cells to the immature dendritic cells to maturing the immature dendritic cells; and a step of adding IP-10(interferon-gamma inducible protein-10) to the matured dendritic cells.