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Peptide analogue with high antibacterial and anti-inflammatory activities designed from Papiliocin peptide
Peptide analogue with high antibacterial and anti-inflammatory activities designed from Papiliocin peptide
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机译:由Papiliocin肽设计的具有高抗菌和抗炎活性的肽类似物
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摘要
PURPOSE: A novel derivative of papiliocin isoalted from Papilio xuthus larva is provided to ensure antibacterial activity against gram negative bacteria and gram positive bacteria. CONSTITUTION: A peptide is selected from sequence numbers 1-2. A pharmaceutical composition contains the peptide as an active ingredient without toxicity to human erythrocytes or mammal normal cells. An antibacterial composition against microorganisms contains a peptide selected among sequence numbers 1 and 2 as an active ingredient. The microorganisms are gram positive bacteria, gram negative bacteria, or antibiotics resistant strain. An anti-inflammatory composition contains the peptide of sequence number 1 as an active ingredient.
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