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Evaluation of acne progress based on quantification of DHEA sulfate and cholesterol sulfate in hair

机译:基于定量头发中硫酸脱氢表雄酮(DHEA)和硫酸胆固醇的评估痤疮的进展

摘要

The invention and the hair was hydrolyzed under a basic condition , triethylamine buffer solution as a developing solvent analyzing the mixture to remove the interfering substance and the analyte concentration , and then , by supplying a solution of triethylamine and acetonitrile as a developing solvent , and elute the analyte liquid chromatography- mass spectrometry with the concentration of the hair at the same time within the DHEA sulfate and cholesterol sulfate, measured, relates to a method of analysis compared the density of hair in DHEA sulfate and cholesterol sulfate, which is differentiated according to the degree of acne disorders . Accordingly, the present invention is expected to be applied shall be able to assess how the disease acne with hair . ;
机译:本发明和头发在碱性条件下被水解,用三乙胺缓冲液作为展开剂分析混合物,去除干扰物质和分析物浓度,然后通过提供三乙胺和乙腈溶液作为展开剂进行洗脱分析物液相色谱-质谱法,同时测定DHEA硫酸盐和胆固醇硫酸盐中头发的浓度,该分析方法涉及一种比较DHEA硫酸盐和胆固醇胆固醇硫酸盐中头发密度的分析方法,根据痤疮的程度。因此,预期将被应用的本发明将能够评估该疾病如何使头发痤疮。 ;

著录项

  • 公开/公告号KR101152655B1

    专利类型

  • 公开/公告日2012-06-05

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20100058131

  • 发明设计人 최만호;조성희;정봉철;

    申请日2010-06-18

  • 分类号G01N30/04;G01N30/72;G01N31/20;A61B10/00;

  • 国家 KR

  • 入库时间 2022-08-21 17:07:58

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