METHOD OF PRESUMING THE METABOLISM OF DRUG IN HUMAN LIVER AND LIVER FUNCTION

摘要

The present invention provides a way to accurately predict the effects of the liver metabolism and liver function of the person's medication. ; More specifically non-human chimeric animal and the same kind of non-chimeric animal that has a stem cell populations of human origin with the proliferation in the body, responsible for the stem cell populations liver function substantially chimeric animal, the human complement of acid production of the stem cells administration of the state and, piheom material was defense against attack provides a method for predicting the time zone Objects and hepatic function of the piheom material of the person, characterized in that the comparison analysis of the metabolites of the chimeric animal and the non-chimeric animal.