Pharmaceutical compositions for prevention and treatment of menopausal symptoms or osteoporosis containing the flavan compounds or the pharmaceutically acceptable salts thereof as active ingredient

摘要

The present invention relates to a Plastic half (flavan) compound or a pharmaceutically acceptable containing as an active salts ingredient menopausal syndrome or pharmaceutical composition for the prevention and treatment of osteoporosis, is Playa bangye compounds of the invention the estrogen receptor gene transfer activity for the estrogen receptor, and denotes a ligand of the estrogen receptor binding activity, by inducing an estrogen-sensitive breast cancer cell proliferation in a concentration-dependent manner shows the estrogenic activity. As phytoestrogens The side effects relief because it indicates a more selective activity at the the estrogen activity of estrogen receptor alpha (ER- ) than estrogen receptor beta (ER- ) as, menopausal useful in syndrome or osteoporosis, preventing and treating may be used. ;