NATURAL ANTIMICROBIAL TOOTHPASTE CONTAINING MICROCAPSULE IN ISOTHIOCYANATES EXTRACTED FROM HORSERADISH BY DISTILLED EXTRACTION PROCESS

摘要

PURPOSE: An antibacterial tooth paste containing isothiocyanates(ITCs) isolated from Horseradish is provided to stabilize antibacterial activity. CONSTITUTION: A method for preparing isothiocyanate-containing solid lipid microcapsule comprises: a step of dispersing isothiocyanate to a solid lipid in a proper concentrate; a step of control aryl isothiocyanate content; a step of disperse the extract at 60C; a step of mixing the solid lipid and water in a ratio of 1:9 and mixing with surfactant; a step of dispersing the mixture with a homogenizer for 30 seconds to form emulsion; a step of cooling the emulsion at 0C. The surfactant is non-ionic surfactant and solid lipid is hydrogenated palm oil.