A NEW DERIVATIVE KATEKHINA, PHARMACEUTICAL COMPOSITION CONTAINING A DERIVATIVE KATEKHIN, APPLICATION OF A DERIVATIVE KATEKHIN AND APPLICATION OF A PHARMACEUTICAL COMPOSITION

摘要

1. The compound represented by General formula (I):! ! or a pharmaceutically acceptable salt thereof,! where R1 and R2 are each independently a hydrogen atom, a lower acyl group, a lower alkoxycarbonyl group, an aralkylcarbonyl group or —C (O) NR11R12, or R1 and R2 are combined to form —C (O) - or a lower alkylene group ; ! R3 represents:! a) a halogen (lower) alkyl group; ! b) a lower acyl group; ! c) a halogen (lower) alkylcarbonyl group; ! d) a cycloalkylcarbonyl group; ! e) an arylcarbonyl group, where the ring of the arylcarbonyl group is unsubstituted or substituted by 1-5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halogen (lower) alkyl group, a lower alkoxy group, a cycloalkyl (lower) alkoxy group, a hydroxy group , lower alkoxycarbonyl group, —C (O) NR11R12 and a cyano group,! f) a heteroarylcarbonyl group, where the ring of the heteroarylcarbonyl group is unsubstituted or substituted by 1-3 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halogen (lower) alkyl group and a lower alkoxy group,! g) an aralkylcarbonyl group, where the ring of the aralkylcarbonyl group is unsubstituted or substituted by 1-5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halogen (lower) alkyl group and a lower alkoxy group,! h) an aryloxy (lower) alkyl carbonyl group, wherein the ring of the aryloxy (lower) alkyl carbonyl group is unsubstituted or substituted by 1-5 substituents selected from the group consisting of a halogen atom, a lower alkyl group, a halogen (lower)