METHOD FOR PRODUCING substrates with a multilayer coating based on polyelectrolyte microcapsules containing biologically active materials

摘要

1. A method for producing a multilayer coating comprising the biologically active components fixed on a substrate, comprising forming a polyelectrolyte microcapsules comprising a core of biologically active composition of matter and the shaping component, applying a first polyelectrolyte multilayer on a substrate, applying an intermediate layer of microcapsules containing multiple polyelectrolyte layers on the first multilayer, depositing a second polyelectrolyte multilayer on the surface of the microcapsules, forming together with first multilayers and an intermediate layer of a multilayer coating microcapsules removing mold component of an inner microcapsule volume, characterized in that the dissolving and removing mold component from microcapsule mounted substrate position with the deposited multilayer coating so that the substrate occupies the upper position with respect to the multilayer coating that allows the output enable solute molecules mold component from the scope of microcapsules not only as by diffusion, but by the action of gravity, the inclination of the substrate, relative to a horizontal surface is selected in the range of 0 to 90 °. ! 2. A method according to claim 1, characterized in that the amount and composition of the layers that are applied over the nuclei selected organo formula: PSS- (PAH-PSS) n, n = 1-7. ! 3. A method according to claim 1, characterized in that the amount and composition of the layers that are applied over the nuclei selected organo formula: PSS- (PAH-PSS) n, n = 1-3. ! 4. A method according to claim 1, characterized in that the amount and composition of the layers that are applied over the body