AUTOMATED SYSTEM FOR PRODUCING MULTILAYER microcellular polyelectrolyte nanocoating to biologically active materials

摘要

The invention relates an apparatus for manufacturing substrates containing microcapsules of biologically active materials based on nano microcellular polyelectrolyte.; An object is to expand the possibilities of installation due to the concurrent deposition of polyionic layers and layers of microcapsules with simultaneous formation of a number of multilayer coatings on substrates.; : The installation comprises a displaceable relative to tanks with solutions of polyelectrolytes platform on which has from 1 to M holders substrates unit for applying microcapsules containing from 1 to M distribution heads, at least one container with an emulsion comprising microcapsules having biologically active components, organic-solvent reservoir nuclei microcapsules. Thus tanks polyionic solution, wash solution and solvent microcapsule core and applying microcapsules assembly mounted on the base parallel to the axis along which the platform in the upper part of the platform above the surface of the tank has pivots adapted to their reciprocal rotation through an angle of 0 to 360 degrees. On rotary axes are secured to the substrate holder. Distribution heads are fixed, or with the possibility of reciprocating movement along the center axes of the substrate and arranged over the working surface of the substrates during deposition of microcapsules onto the substrate. Material of the active substance included in the microcapsule is selected from the group consisting of proteins, enzymes, antibodies, DNA fragments .. nc 1, ZP 2, 6 yl.