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METHOD OF PREDICTING OVERALL SURVIVAL OF PATIENTS WITH MULTIPLE MYELOMA

机译:预测多发性骨髓瘤患者总生存率的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to field of medicine, in particular to oncohematology. In order to predict overall survival of patients with multiple myeloma, as factors of unfavourable prognosis used are levels of β2-microglobulin and creatinine in blood serum, patient's sex and immunochemical version of multiple myeloma. Level of β2-microglobulin ≥5.7mg/l is evaluated as 2 points, level of creatinine ≥110 mcmol/l - as 1 point, female sex of patient - as 1 point, IgA immunochemical version of multiple myeloma - as 1 point. Absence of each of said factors is evaluated as 0 points. In group of low risk with sum of points 0-1 overall survival within 46 months is predicted. In group of intermediate risk with sum of points 2-3 overall survival within 27 months is predicted. In group of high risk with sum of points 4-5 overall survival within 9 months is predicted.;EFFECT: method makes it possible to predict course of multiple myeloma;4 dwg, 1 ex, 2 tbl
机译:技术领域本发明涉及医学领域,尤其涉及肿瘤血液学。为了预测多发性骨髓瘤患者的总体生存率,使用了血清中β 2 -微球蛋白和肌酐的水平,患者的性别和多发性骨髓瘤的免疫化学形式,作为预后不良的因素。 β 2 -微球蛋白≥5.7mg/ l的水平为2分,肌酐≥110mcmol / l的水平为1分,患者的女性为1分,IgA免疫化学多发性骨髓瘤-为1分。每个所述因素的缺失被评估为0分。在总分为0-1的低风险组中,可以预测46个月内的总体生存率。在具有2-3点总和的中等风险组中,可以预测27个月内的总体存活率。在高危人群中,预测9个月内总生存期为4-5分的总生存率。效果:该方法可以预测多发性骨髓瘤的病程; 4 dwg,1 ex,2 tbl

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