NONIMMUNOSUPPRESSIVE CYCLOSPORINE FOR TREATING CONGENITAL ULLRICH MYOPATHY

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to medicine and concerns the use of a non-immunosuppressive derivative of cyclosporine A for reducing mitochondrial dysfunction and a degree of apoptosis in patient's cells with diagnosed congenital Ullrich myopathy or Bethlem myopathy.;EFFECT: invention provides considerable reduction of a degree of apoptosis and mitochondrial dysfunction.;5 cl, 5 ex, 6 dwg, 1 tbl