USE OF MONOCLONAL ANTIBODIES SPECIFIC TO O-ACETYLATED FORM OF GANGLIOSIDE GD2 FOR TREATING CERTAIN FORMS OF CANCER

摘要

FIELD: medicine.;SUBSTANCE: what is offered is the use of monoclonal antibodies recognising the O-acetylated form of ganglioside GD2 and not recognising ganglioside GD2 for treating cancer characterised by O-acetylated GD2 expression, particularly neuroectodermal tumours, as well as the use of said antibody related to a toxic molecule, a drug or a second antibody for treating cancer characterised by O-acetylated GD2 expression.;EFFECT: use of the invention can find further application in treating cancer.;13 cl, 16 ex, 16 dwg