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METHOD OF TREATING DIFFUSE MYOCARDIAL DAMAGE

机译:治疗弥漫性心肌损伤的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, specifically cardiology and cardiosurgery, and may be used for treating diffuse myocardial damage. That is ensured by cell sampling of mononuclear fraction of bone marrow in number of 10 mln cells. The 5 mln cells are introduced by aortic puncture between a coronary artery mouth and a short-term clamping point in an ascending section to a junction to a common carotid artery. The rest 5 mln cells are introduced by two injections. The first 2.5 mln cells are introduced in an apex of the left ventricular myocardium, while the second 2.5 mln cells are introduced into a side wall of the left ventricular myocardium.;EFFECT: method provides functional recovery of the damaged myocardium ensured by the enlarged area of the microvasculature in an ischemic segment of muscular tissue due to formation of local permanent loci of angiogenesis ensured by maximum cell accumulation for the first hour after transplantation and minimum escape from the myocardium for the first 20 hours after the combined introduction.;3 tbl
机译:技术领域本发明涉及医学,特别是心脏病学和心脏外科手术,并且可以用于治疗弥漫性心肌损伤。这是通过对1000万个细胞中的骨髓单个核部分进行细胞采样来确保的。通过主动脉穿刺将500万个细胞引入冠状动脉口和上升段中的短期钳位点之间,以连接到颈总动脉。通过两次注射引入其余的500万个细胞。前250万个细胞被引入左心室心肌的顶端,而后250万个细胞被引入左心室心肌的侧壁。效果:该方法可通过扩大面积确保受损心肌的功能恢复局部肌肉血管形成的局部永久性基因座形成,从而在肌肉组织的局部缺血中形成微血管,其通过移植后第一小时的最大细胞蓄积和联合引入后的前20小时的心肌最小逃逸得以确保; 3 tbl

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