RECOMBINANT PLASMID DNA pPBS-St9 CODING SOMATOTROPIN POLYPEPTIDE, AND SACCHAROMYCES CEREVISIAE YEAST STRAIN FOR PRODUCING RECOMBINANT SOMATOTROPIN

摘要

FIELD: medicine.;SUBSTANCE: what is presented is recombinant plasmid DNA pPBS-St9 coding polypeptide having a sequence of the human growth hormone somatotropin of molecular weight 4.1 MDa (6266 base pairs), as well as the Saccharomyces cerevisiae strain BY4739 [leu2 ura3 lys2 prcl::LEU]/pPBS-St9 containing recombinant plasmid DNA pPBS-St9 that is a recombinant somatotropin producer.;EFFECT: invention may be used for producing the recombinant human growth hormone in treating dwarfism.;2 cl, 5 dwg, 2 ex