Liposomes that stimulate the intracellular penetration of drugs, their use for the preparation of topical pharmaceutical or cosmetic compositions containing these liposomes and a screening method for finding substances to stimulate intracellular penetration

摘要

Use of liposomes, characterized in that they comprise, at least in part in their structure, a substance or a mixture of substances which is / are capable of intracellular penetration of at least one active substance which is present in or promotes the liposomes is stimulated, and which is selected from the group consisting of: a) a primary, secondary, tertiary or quaternary fatty monoamine comprising a single C10 to C13 fat chain; or b) a solution of quaternized plant proteins of the formula of the type R-N (R1R2R3), where R symbolizes the plant protein molecule; R1 and R2 are independently a C1-C6 hydrocarbon group and R3 is an alkyl radical having 10 to 18 carbon atoms; as a cosmetic agent that stimulates the intracellular penetration of at least one active ingredient, for producing a topical cosmetic composition; or for the manufacture of a topical pharmaceutical composition.