A method for carrying out of the beam the form of shock activated dissociation in the already existing ions injection path of a mass spectrometer

摘要

Herein, methods and systems described, the use of the already existing ions injection path of a mass spectrometer for carrying out of the beam the form of shock activated dissociation, as well as other dissociation methods relate to. The method, using a large selection of the mass spectrometer configurations are exerted and permit the execution of msⁿ-Experiments on very elementary mass spectrometers, even those without secondary mass analyzers and / or impact chambers. After the injection and the selection of a certain ion type or a certain ions population, this population by means of beam the form of shock activated dissociation (collision - activated dissociation, cad) as well as other dissociation a method wherein the already existing ions injection path or of the inlet of a mass spectrometer is used. In the case of cad - applications, this is, for example, by means of the ions is transmitted back along the ion injection path with a high kinetic energy massan achieved. While the ions in the regions which are under a higher pressure, which are located in or in the vicinity of the atmospheric pressure - inlet, are fragmented and then the ions trapped. After the activation and the trapping, the ions may be either in the primary ions in the direction of selection reinjected or are sent to a secondary mass analyzer.