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CYTOLOGY METHOD USING AUTOFLUORESCENCE OF WHITE GLOBLES FOR EARLY DIAGNOSIS AND FOLLOW-UP OF INFECTIONS

机译:利用白色荧光粉自发荧光进行早期诊断和感染随访的细胞学方法

摘要

The present invention relates to an in vitro method for diagnosing the infectious state of an individual from a sample of white blood cells from a biological sample of an organ potentially infected with a pathogenic microorganism of said individual, comprising at least one least the two following steps: i) measure the average cellular intensity of the autofluorescence of said sample, and ii) compare the intensity measured in step i) with a control value, so as to determine the infectious state of said individual . The diagnostic method of the invention uses routine optical equipment to work in wavelength ranges compatible with cellular autofluorescence, and thus provides a fast, reliable and inexpensive aid to the diagnosis or monitoring of a infection in an individual.
机译:本发明涉及一种用于从白细胞样品中诊断个体的感染状态的体外方法,所述白细胞样品来自可能感染了该个体的病原性微生物的器官的生物样品,该方法至少包括以下两个步骤中的至少一个:i)测量所述样品的自发荧光的平均细胞强度,并且ii)将在步骤i)中测量的强度与对照值进行比较,以确定所述个体的感染状态。本发明的诊断方法使用常规的光学设备在与细胞自发荧光兼容的波长范围内工作,因此为诊断或监测个体中的感染提供了快速,可靠和廉价的帮助。

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