PEPTIDYL-ARGININE 1 AND / OR 3 EPIDERM ACTIVATOR COMPOUNDS IN EPIDERM AND USES THEREOF

摘要

The present invention relates to the activation of peptidyl-arginine deiminases (PADs) 1 and / or 3 in the epidermis by at least one active agent, used alone or in combination, namely caffeine, acefylline and / or theobromine in a cosmetic and / or pharmaceutical composition. The subject of the present invention is also the use, especially in cosmetics and / or therapeutic, of the above-mentioned active agents, alone or in combination, to improve the barrier functions of the epidermis, to prevent and / or treat the symptoms related to drought. cutaneous or improve and / or promote the hydration of the stratum corneum. Finally, the invention relates to increasing the activity of PAD1 and / or PAD3 in the epidermis.