首页> 外国专利> Enhanced bioavailability of octreotide vis the GI tract using a suspension in a hydrophobic medium

Enhanced bioavailability of octreotide vis the GI tract using a suspension in a hydrophobic medium

机译:使用疏水性介质中的悬浮液,奥曲肽相对于胃肠道的生物利用度提高

摘要

The invention relates to a composition comprising a suspension which comprises an admixture of a hydrophobic medium and a solid form wherein the solid form comprises a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid, and wherein the medium chain fatty acid salt is present in the composition at an amount of 10% or more by weight, wherein the therapeutic agent is a polypeptide. The invention also relates to compositions for use in treating or preventing diseases by administration of the compositions to affected subjects.
机译:本发明涉及包含悬浮液的组合物,所述悬浮液包含疏水性介质和固体形式的混合物,其中所述固体形式包含治疗有效量的治疗剂和至少一种中链脂肪酸的盐,并且其中所述介质链脂肪酸盐在组合物中的存在量为10重量%或更多,其中治疗剂是多肽。本发明还涉及通过将组合物施用于受影响的受试者来治疗或预防疾病的组合物。

著录项

  • 公开/公告号GB2463978B8

    专利类型

  • 公开/公告日2012-02-29

    原文格式PDF

  • 申请/专利权人 CHIASMA INC;

    申请/专利号GB20090016349

  • 申请日2009-09-17

  • 分类号A61K9/10;A61K38/14;A61K38/16;A61K38/21;A61K38/26;A61K38/31;A61K47/12;A61K47/14;A61P3;A61P3/04;A61P31;A61P35;A61P37;

  • 国家 GB

  • 入库时间 2022-08-21 17:03:33

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号