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Lunch Biot tic peptide-based apoptosis imaging agent

机译:基于午餐生物肽的细胞凋亡显像剂

摘要

The present invention relates to a radiopharmaceutical imaging of apoptosis in vivo. The present invention provides an imaging agent that targets the apoptotic cells by selective binding phosphatidylethanolamine aminophospholipids are exposed on the surface of apoptotic cells to (PE). Radiopharmaceutical contains a radioactive metal complex of the chelator conjugate of PE-binding peptide. The radiopharmaceutical composition, in vivo imaging methods and kits are also provided. None [Selection Figure]
机译:本发明涉及体内细胞凋亡的放射性药物成像。本发明提供了通过选择性结合磷脂酰乙醇胺氨基磷脂而将其靶向凋亡细胞的显像剂,该磷脂在凋亡细胞的表面上暴露于(PE)。放射性药物包含PE结合肽的螯合剂缀合物的放射性金属络合物。还提供了放射性药物组合物,体内成像方法和试剂盒。无[选择图]

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