D-serine dehydratase and its utilization

摘要

Problem to be solved: to provide a novel D-serine determination method to solve various problems in the current D-serine determination method. In addition, to provide a novel enzyme used in the D-serine assay, and the gene encoding it. (a) a novel D-serine consisting of a protein having an amino acid sequence represented by sequence number 1 or an amino acid sequence homologous to an amino acid sequence indicated by sequence number 1 and having a D-serine dehydratase activity Hydratase is provided. Also, a D-serine determination method is provided which quantifies ammonia or pyruvic acid resulting from the reaction of the enzyme to the sample and calculates the D-serine amount in the sample from the quantitative value.