Evaluation method and screening method of substance having activity to mitigate adverse effects of drugs, and side effect relaxant having substances identified by these methods as active components

摘要

PPROBLEM TO BE SOLVED: To provide a method for efficiently and easily evaluating and screening the substance for alleviating the side effect of a medicine on an organism having an acquired immunological mechanism, and a side effect alleviating agent for alleviating the side effect of the medicine on the organism having the acquired immunological mechanism by utilizing the substance evaluated and screened by that method. PSOLUTION: The evaluation method includes the process (a) of admistering the medicine and a substance to be examined to the organism having only a natural immunological mechanism, the process (b) of detecting the side effect of the medicine on the organism having the natural immunological mechanism and the process (c) of evaluating whether the substance to be examined alleviates the side effect and the screening method further includes the process (d) of selecting the substance evaluated to alleviate the side effect. The side effect alleviating agent contains edible oil as an effective component to alleviate the side effect of the medicine. PCOPYRIGHT: (C)2008,JPO&INPIT