Role of N-2-hydroxy-ethyl-piperazine-N'-2-ethanesulfonic acid (HEPES) in pain control and recovery of demyelinating injury

摘要

Compositions and therapeutic uses of HEPES and derivatives in the treatment of pain associated with cancers and side-effects including post-chemotherapy cognitive impairment are disclosed herein. HEPES is also used to treat neurodegenerative and neurological diseases, demyelinization injuries, and side-effects and withdrawal symptoms associated with benzodiazepines, anti-depressants, and other neurological agents.