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Novel porphyrin derivatives, especially chlorin and / or bacteriochlorin, and their application in photodynamic therapy
Novel porphyrin derivatives, especially chlorin and / or bacteriochlorin, and their application in photodynamic therapy
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机译:新型卟啉衍生物,特别是二氢卟酚和/或细菌绿素,及其在光动力治疗中的应用
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摘要
The invention relates to derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, which can be used in photodynamic therapy. According to the formulas of the invention, X1, X2, X3, X4, X5, X6, X7, X8, which may be identical or different, each represent halogen atoms or hydrogen atoms. R1, R2, R3, R4, which may be identical or different, are each selected from the following groups: -OH, amino acids, -OR and -NHR and/or a chlorine atom, wherein R is an alkyl group having between 1 and 12 carbon atoms. The invention also relates to an anticancer and/or antiviral and/or antimicrobial medicament for human or animal use, which contains one or more compounds as the main active ingredient.
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