The enantio choice acylation which uses the lipase catalytic converter with the precipitation after that by sulfuric acid, the 4 of the racemic body (the 1 aminoethyl) from benzoic acid methyl ester (R) - and (S) the 4 (1 ammonium ethyl) the manner which prepares the benzoic acid methyl ester sulfate

摘要

A method for preparing optically active methyl 4- (1-ammoniumethyl) benzoate sulfate by reacting racemic methyl 4- (1-aminoethyl) benzoate with an acylating agent in the presence of a lipase to give methyl 4- (1-aminoethyl) benzoate and subsequently precipitating methyl 4- (1-ammoniumethyl) benzoate sulfate by adding sulfuric acid.