Inside the production mannered null addA gene,

摘要

PROBLEM TO BE SOLVED: To improve secretion productivity in such a microorganism as used as a host for producing a substance.;SOLUTION: Provided is a microorganism in which at least one of a nuclease-related gene of Bacillus subtilis and a gene corresponding to the gene is deleted or inactivated. Especially, the nuclease-related gene is preferably an endogenous nuclease-related gene. The endogenous nuclease-related gene includes addA gene, addB gene, sbcD gene, xseA gene, xseB gene and nucB gene.;COPYRIGHT: (C)2009,JPO&INPIT