首页> 外国专利> Method for presensitizing cancer prior to treatment with radiation and / or chemotherapy and novel cytokine mixtures

Method for presensitizing cancer prior to treatment with radiation and / or chemotherapy and novel cytokine mixtures

机译:在放射和/或化学疗法和新型细胞因子混合物治疗前对癌症进行预敏的方法

摘要

This invention relates to a breakthrough method for pre-sensitizing cancer prior to a therapeutic treatment such as chemotherapy, radiation therapy or immuno-therapy and a novel cytokine mixture used in the method thereof. The cytokine mixture is a serum-free and mitogen-free mixture comprised of specific ratios of cytokines such as IL-1beta, TNF-alpha, IFN-gamma and GM-CSF to Interleukin 2 (IL-2), which is effective in inducing cancerous cells to enter a proliferative cell cycle phase thereby increasing their vulnerability to chemotherapy, radiation therapy and immuno-therapy. One such novel cytokine mixture is Leukocyte Interleukin Injection (LI) or Multikine(R), which can be used alone or in combination with other drugs for the treatment of cancer thereby increasing the success of cancer treatment and the disease free survival of cancer patients.
机译:本发明涉及在治疗方法如化学疗法,放射疗法或免疫疗法之前使癌症预敏化的突破性方法,以及在该方法中使用的新型细胞因子混合物。细胞因子混合物是无血清和无促分裂原的混合物,由特定比例的细胞因子(如IL-1β,TNF-α,IFN-γ和GM-CSF)与白介素2(IL-2)组成,可有效诱导癌细胞进入增殖细胞周期阶段,从而增加了它们对化学疗法,放射疗法和免疫疗法的脆弱性。一种这样的新型细胞因子混合物是白细胞白介素注射液(LI)或Multikine,其可以单独使用或与其他药物组合用于治疗癌症,从而增加癌症治疗的成功率和癌症患者的无病生存期。

著录项

  • 公开/公告号JP5122279B2

    专利类型

  • 公开/公告日2013-01-16

    原文格式PDF

  • 申请/专利权人 セル‐サイ コーポレイション;

    申请/专利号JP20070519321

  • 发明设计人 テイラー;アヤル;

    申请日2005-06-28

  • 分类号A61K38;A61K38/21;A61P35;

  • 国家 JP

  • 入库时间 2022-08-21 16:56:09

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