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Stability of amurojipin liquid medicine and jello medicine

机译:阿莫罗平液体药和果冻药的稳定性

摘要

PROBLEM TO BE SOLVED: To provide a stable liquid preparation and jelly preparation of amlodipine.;SOLUTION: This stable liquid preparation in pH 5 to 7 range liquid property is prepared by using an anionic surfactant having a sulfuric acid group or a sulfonic acid group as a stabilizer of the amlodipine in its solution. Further, by adding a gelling agent, fine powdery solid and a gelation-regulating agent, and then mixing, the objective stable jelly composition of the amlodipine, having a high quick disintegrating property can be prepared. Thereby, the preparations easy for taking can be provided for aged persons having a decreased swallowing function and becoming difficult to take tablet preparations.;COPYRIGHT: (C)2009,JPO&INPIT
机译:解决的问题:提供氨氯地平的稳定的液体制剂和果冻制剂。解决方案:通过使用具有硫酸基团或磺酸基团的阴离子表面活性剂制备pH值在5至7范围内的这种稳定的液体制剂。氨氯地平在溶液中的稳定剂。此外,通过添加胶凝剂,细粉状固体和胶凝调节剂,然后混合,可以制备具有高快速崩解性的氨氯地平的目标稳定的胶冻组合物。因此,可以为吞咽功能降低并且难以服用片剂的老年人提供易于服用的制剂。;版权所有:(C)2009,JPO&INPIT

著录项

  • 公开/公告号JP5072748B2

    专利类型

  • 公开/公告日2012-11-14

    原文格式PDF

  • 申请/专利权人 株式会社 メドレックス;

    申请/专利号JP20080178569

  • 发明设计人 ▲浜▼本 英利;辰巳 昇;遠藤 充;

    申请日2008-07-09

  • 分类号A61K31/4422;A61K47/20;A61K9/107;A61K47/26;A61K47/12;A61K47/10;A61K47/02;A61K47/36;A61K47/38;A61P9/10;A61P9/12;A61P9/04;A61P9/00;

  • 国家 JP

  • 入库时间 2022-08-21 16:56:09

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