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7-azaindole derivatives and their use in inhibiting c-Jun N-terminal kinase

机译:7-氮杂吲哚衍生物及其在抑制c-Jun N端激酶中的应用

摘要

The present invention provides a compound of formula (I); or a pharmaceutically acceptable salt thereof, the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof in the inhibition of c-Jun N-terminal kinase (JNK) activity and the use in medicine and particularly in the treatment of neurodegenerative disorders, inflammatory diseases and/or and autoimmune diseases. The invention also provides processes for the manufacture of said compounds of formula (I) or a pharmaceutically acceptable salt thereof and compositions containing them.
机译:本发明提供式(I)的化合物;或其药学上可接受的盐,式(I)化合物或其药学上可接受的盐在抑制c-Jun N末端激酶(JNK)活性中的用途以及在医学中,特别是在神经退行性疾病的治疗中的用途疾病,炎性疾病和/或自身免疫性疾病。本发明还提供了制备所述式(I)化合物或其药学上可接受的盐的方法以及包含它们的组合物。

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