首页> 外国专利> Identification method of oncogene, establishment method of oncogene revelation cell, and screening method of oncogene target medicine

Identification method of oncogene, establishment method of oncogene revelation cell, and screening method of oncogene target medicine

机译:癌基因的鉴定方法,癌基因揭示细胞的建立方法以及癌基因靶药的筛选方法

摘要

This invention offers the methodology which can develop the anti- cancer medicine which is superior than past vis-a-vis the various cancer. Concretely, as for this invention, the cancer cell, is processed with the manifestation vector of the imported oncogene, the cancer cell which was processed next with the manifestation vector, the fact that it cultures under the condition for obstructing the revelation or function of the oncogene which is specific to the said cancer cell is included, establishment method of the artificial cell, and the artificial cell which is established; The fact that you appraise whether or not the test substance obstructs the multiplication of the above-mentioned artificial cell, is included, screening method of the anti- cancer medicine; And, the cancer cell, is processed with the manifestation vector of the test gene, the cancer cell which next, was processed with the manifestation vector, the fact that it cultures under the condition for obstructing the revelation or function of the oncogene which is specific to the said cancer cell is included, identification method of the oncogene is offered.
机译:本发明提供了可以开发抗癌药物的方法学,该抗癌药物相对于各种癌症而言是过去的。具体地,对于本发明,用导入的癌基因的表达载体处理癌细胞,随后用表达载体处理的癌细胞,其在阻碍细胞的揭示或功能的条件下进行培养。包括对所述癌细胞具有特异性的癌基因,人造细胞的建立方法以及所建立的人造细胞。抗癌药物的筛选方法包括评估被测物质是否阻碍上述人工细胞的增殖。并且,用测试基因的表达载体处理癌细胞,然后用表达载体处理癌细胞,其在阻碍特异性癌基因的揭示或功能的条件下进行培养。对上述癌细胞包括在内,提供了癌基因的鉴定方法。

著录项

  • 公开/公告号JPWO2011102507A1

    专利类型

  • 公开/公告日2013-06-17

    原文格式PDF

  • 申请/专利权人 富士レビオ株式会社;

    申请/专利号JP20120500678

  • 发明设计人 伊勢 伸之;南原 大介;小見 和也;

    申请日2011-02-21

  • 分类号C12N5/10;C12N15/09;C12Q1/02;C12Q1/48;C12Q1/68;

  • 国家 JP

  • 入库时间 2022-08-21 16:54:31

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