Triterpene derivative and drug for prevention or treatment of chronic hepatitis C

摘要

Provided are a triterpene derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof, and a drug for preventing or treating chronic hepatitis C containing the same as an active ingredient. [In the formula (I), R1 represents a carboxyl group, a hydroxymethyl group, -CH2OSO3H, or ## STR2 ## and R2 represents -OR3 or -O- (CH2) m-OR4. Here, R3 is a hydroxymethyl group, a dimethylaminomethyl group, a phenylaminomethyl group, a morpholinomethyl group, a benzyl group optionally substituted with a carboxyl group or a formyl group, a C1-6 alkyl group, a C2-6 alkenyl group, A C2-6 alkynyl group or a hydroxy C1-6 alkyl group is represented, R4 represents a phenyl group which may be substituted with a carboxyl group, and m represents an integer of 1 to 3. However, it excludes when R1 is -CH2OH and R3 is a C1-6 alkyl group, a C2-6 alkenyl group or a benzyl group. ]