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BABESIA MICROTI GENOMIC CLONES CONTAINING NOVEL ANTIGENS USEFUL IN THE DIAGNOSIS OF BABESIOSIS

机译：含有新型抗原的巴贝斯菌基因组在巴贝斯虫病诊断中的应用

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摘要

Disclosed are the cloning and expression of novel antigens in Babesia microti. The recombinant polypeptides are highly immunogenic. The polypeptides of the present invention provide the basis of a diagnostic assay that is sensitive, rapid and accurate using patient's sera. Also disclosed is an IgG and IgM ELISA using two novel recombinant antigens in the diagnosis of Babesia infection.

机译：公开了小巴贝氏菌中新抗原的克隆和表达。重组多肽是高度免疫原性的。本发明的多肽提供了使用患者血清进行灵敏，快速和准确的诊断测定的基础。还公开了使用两种新型重组抗原的IgG和IgM ELISA诊断 Babesia 感染的方法。 展开▼

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公开/公告号US2013177941A1

专利类型

公开/公告日2013-07-11

原文格式PDF

申请/专利权人 JOHN G. HOEY;HANNAH VENIT;MARTIN E. ADELSON;ELI MORDECHAI;FERNANDO VALOIS-CRUZ;
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申请/专利号US201213713155

发明设计人 MARTIN E. ADELSON;FERNANDO VALOIS-CRUZ;ELI MORDECHAI;HANNAH VENIT;JOHN G. HOEY;
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申请日2012-12-13

分类号C07K14/44;

国家 US

入库时间 2022-08-21 16:52:28

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