METHOD FOR TREATING IRRITABLE BOWEL SYNDROME BY ADMINISTRATION OF CHLORIDE CHANNEL OPENER

摘要

A chloride channel opener, especially a prostaglandin compound, is used for the treatment of functional gastrointestinal disorders. The prostaglandin compound can be, for example, a 13,14-dihydro-15-keto-16,16-difluoro-prostaglandin E₁ compound or 13,14-dihydro-15-keto-16,16-difluoro-18-methyl-prostaglandin E₁ compound. The functional gastrointestinal disorders can be, for example, irritable bowel syndrome and/or functional dyspepsia. The treatment can include, for example, systemic administration 1-4 times per day or continuous administration of the compound in an amount of 0.01-100 μg per day.