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TREATMENT MODALITIES TO PREVENT OR TREAT LOSS OF CARDIOVASCULAR FUNCTION IN AGING HUMANS
TREATMENT MODALITIES TO PREVENT OR TREAT LOSS OF CARDIOVASCULAR FUNCTION IN AGING HUMANS
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机译:预防或治疗老年人心血管功能丧失的治疗方法
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摘要
Provided herein are methods for treating, preventing or reducing age related vascular stiffness and impaired cardiovascular function in a subject comprising administering to the subject a therapeutic amount of IL-10 or an IL-10 agonist or pharmaceutical compositions comprising the same. Also included herein are methods for determining whether a biologically active agent can treat, prevent or reduce age related vascular stiffness and impaired cardiovascular function using an in vitro model in a IL-10 knockout IL-10(tm/tm) mouse which lacks IL-10 function.
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