ZEBRAFISH SEIZURE MODEL, METHOD FOR ESTABLISHING THE SAME, AND METHOD FOR SCREENING ANTIEPILEPTIC DRUG USING THE SAME

摘要

A zebrafish seizure model, a method for establishing the same, and a method for screening for antiepileptic drug using the same are disclosed. The method for establishing the zebrafish seizure model comprises the following steps: placing a zebrafish in a medium containing an inducing compound represented by the following formula (I) to induce seizure-like symptom in zebrafish:; wherein, the definitions of R₁, R₂, R₃ are the same as those defined in the specification.