首页> 外国专利> FUNCTIONALIZED GRAPHENE OR GRAPHENE OXIDE NANOPORE FOR BIO-MOLECULAR SENSING AND DNA SEQUENCING

FUNCTIONALIZED GRAPHENE OR GRAPHENE OXIDE NANOPORE FOR BIO-MOLECULAR SENSING AND DNA SEQUENCING

机译:功能化石墨烯或氧化石墨烯纳米用于生物分子传感和DNA测序

摘要

A technique for a nanodevice is provided. A reservoir is separated into two parts by a membrane. A nanopore is formed through the membrane, and the nanopore connects the two parts of the reservoir. The nanopore and the two parts of the reservoir are filled with ionic buffer. The membrane includes a graphene layer or a graphene oxide layer. The nanopore could be oxidized to graphene oxide at an inner surface. The graphene or graphene oxide in the nanopore is coated with an organic layer configured to interact with biomolecules in a different way in order to differentiate the biomolecules. The organic layer enhances resolution and motion control of the biomolecules. A time trace of ionic current is monitored to identify the biomolecules based on a respective interaction of the biomolecules with the organic layer.
机译:提供了一种用于纳米器件的技术。储器被膜分成两部分。穿过膜形成纳米孔,并且纳米孔连接储层的两个部分。纳米孔和储液罐的两部分充满了离子缓冲液。该膜包括石墨烯层或氧化石墨烯层。纳米孔可在内表面被氧化成氧化石墨烯。纳米孔中的石墨烯或氧化石墨烯涂覆有有机层,该有机层被配置为以不同的方式与生物分子相互作用,以便区分生物分子。有机层增强了生物分子的分辨率和运动控制。监测离子电流的时间轨迹,以基于生物分子与有机层的相应相互作用来识别生物分子。

著录项

  • 公开/公告号US2013256154A1

    专利类型

  • 公开/公告日2013-10-03

    原文格式PDF

  • 申请/专利权人 HONGBO PENG;

    申请/专利号US201213464165

  • 发明设计人 HONGBO PENG;

    申请日2012-05-04

  • 分类号G01N27/40;G01N33/50;B82Y30/00;B82Y40/00;B82Y5/00;

  • 国家 US

  • 入库时间 2022-08-21 16:50:13

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