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METHOD OF PREPARING SELF-ASSEMBLED EXTRACELLULAR MATRICES AND USE OF SELF-ASSEMBLED EXTRACELLULAR MATRICES FORMED BY USING THE METHOD

机译:自组装细胞外基质的制备方法及使用该方法制成的自组装细胞外基质的使用

摘要

Methods of preparing a self-assembled matrix from cell-derived extracellular matrice, and of inducing cell proliferation and differentiation by using the self-assembled matrix, and applying the self-assembled matrix into cell therapy. In detail, unique extracellular matrices obtained from particular cells are collected and then subjected to decellularization in order to form a self-assembled matrix including nano fibers only formed of extracellular matrix. In addition, the matrix prepared as described above provides a platform that is effective for the induction of the mass proliferation or differentiation of cells, and thus, may be applied in manufacturing cell therapy products.
机译:由细胞衍生的细胞外基质制备自组装基质,并通过使用自组装基质诱导细胞增殖和分化,并将该自组装基质应用于细胞治疗的方法。详细地,收集从特定细胞获得的独特的细胞外基质,然后进行脱细胞,以形成包括仅由细胞外基质形成的纳米纤维的自组装基质。另外,如上所述制备的基质提供了有效诱导细胞大规模增殖或分化的平台,因此可用于制造细胞疗法产品。

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