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Method for Pre-Debriding Treatment of Non-Viable Skin Tissue and Compositions and System Thereof
Method for Pre-Debriding Treatment of Non-Viable Skin Tissue and Compositions and System Thereof
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机译:非活组织和组合物的清创前处理方法及其系统
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摘要
A pre-debriding composition comprises a chaotropic agent, preferably urea, and, preferably, exfoliating and analgesic agents. The pre-debriding composition reduces the collagen denaturation temperature, Tm, at the site of a wound. Use of the composition along with a supply of heat increases the effectiveness of a subsequent enzymatic debriding treatment. A dressing and heating system is also provided for use with the pre-debriding composition. An “instant activated” debriding composition and package is provided comprising a gel composition and a powdered debriding zymogen composition, wherein mixing of the two compositions results in an activated enzymatic debriding composition. 22290368.1
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