首页> 外国专利> RECOVERING NUCLEATED RED BLOOD CELLS AND METHOD FOR CONCENTRATING AND RECOVERING NUCLEATED RED BLOOD CELLS

RECOVERING NUCLEATED RED BLOOD CELLS AND METHOD FOR CONCENTRATING AND RECOVERING NUCLEATED RED BLOOD CELLS

机译:回收有核的红血球以及浓缩和回收有核的红血球的方法

摘要

Provided is a chip or the like having a particulate concentrating mechanism such as a mechanism that can selectively concentrate nucleated red blood cells contained in maternal blood and derived from a fetus and can collect the concentrated liquid rich in nucleated red blood cells, and also provided is a nucleated red blood cell concentrating/collecting method. A micro-channel chip for concentrating nucleated red blood cells has an inlet-side channel, an outlet-side channel, and a separation narrow channel provided between the inlet-side channel and the outlet-side channel. The separation narrow channel has an inner wall having a dimension through which non-nucleated red blood cells easily pass and nucleated red blood cells hardly pass, and has a means for deforming or moving part of the inner wall of the channel to have a dimension through which nucleated red blood cells easily pass. The following are also provided: a method for collecting a liquid in which nucleated red blood cells obtained by using this chip are concentrated; and a micro-channel chip for concentrating particulates other than for concentrating nucleated red blood cells.
机译:本发明提供一种芯片等,其具有能够使母血中所含的胎儿来源的有核红血球选择性地浓缩,能够收集富含有核红血球的浓缩液的机制等颗粒浓缩机制。一种有核红细胞浓缩/收集方法。用于浓缩有核红细胞的微通道芯片具有入口侧通道,出口侧通道和设置在入口侧通道和出口侧通道之间的分离窄通道。分离狭窄通道具有内壁,该内壁具有尺寸,非核红细胞容易通过,而有核红细胞几乎不通过,并且具有用于使通道内壁的一部分变形或移动以具有尺寸的装置。有核红细胞容易通过。还提供以下内容:一种收集液体的方法,该液体中浓缩了使用该芯片获得的有核红细胞;除了浓缩有核红细胞以外,还用于浓缩微粒的微通道芯片。

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