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Use of ursolic acid saponin,oleanolic acid saponin in preparation of increasing leucocytes and/or platelet medicine

机译:熊果酸皂苷,油酸皂苷在制备增加白细胞和/或血小板药物中的用途

摘要

The invention provides the use of ursolic acid saponin and oleanolic acid saponin of formula (I) in preparing medicaments for increasing leucocytes and/or platelets. The invention also provides a pharmaceutical composition containing the same compound. The invention utilizes the cheap and accessible ursolic acid and oleanolic acid which are widely present in natural plants as raw materials, introduces monosaccharyls or oligosaccharyls by structural modification. It is proved by pharmacological tests that the compound of formula (I) have an activity of obviously increasing leucocytes and/or platelets.; embedded image
机译:本发明提供式(I)的熊果酸皂苷和齐墩果酸皂苷在制备用于增加白细胞和/或血小板的药物中的用途。本发明还提供了包含相同化合物的药物组合物。本发明利用天然植物中广泛存在的廉价和可得的熊果酸和齐墩果酸作为原料,通过结构修饰引入单糖基或寡糖基。药理试验证明,式(Ⅰ)化合物具有明显增加白细胞和/或血小板的活性。 “嵌入式图像”

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