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Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
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机译:用于电子和磁感测微流通道内容的方法和装置
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摘要
The presence of a detectable entity within a detection volume of a microfabricated elastomeric structure is sensed through a change in the electrical or magnetic environment of the detection volume. In embodiments utilizing electronic detection, an electric field is applied to the detection volume and a change in impedance, current, or combined impedance and current due to the presence of the detectable entity is measured. In embodiments utilizing magnetic detection, the magnetic properties of a magnetized detected entity alter the magnetic field of the detection volume. This changed magnetic field induces a current which can reveal the detectable entity. The change in resistance of a magnetoresistive element may also reveal the passage of a magnetized detectable entity.
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