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Extramuscular treatment of traumatic-induced migraine headache

机译:创伤性偏头痛的肌外治疗

摘要

A method for selection and treatment of externally caused migraine headache, the method includes identifying a patient group having chronic migraine headache; determining the identified patient group, a specific patient with a post traumatic migraine headache; and administering to the selected patient by injection of a therapeutically effective amount of a Botulinum neurotoxin in a pharmaceutically safe form to the selected patient's head or upper neck; administration preferably being on the sites of the trigeminal cervical system, enabling axonal transport of the neurotoxin from distal to central sites; and the administration preferably comprising extramuscular injection of the neurotoxin of suitable dilution (a) over the aponeurotic fascia, or (b) intra-orally, in a foramina of the sphenopalatine ganglion, or (c) to emerging exit points of nerves including foraminal sites.
机译:一种用于选择和治疗外部引起的偏头痛的方法,该方法包括鉴定患有慢性偏头痛的患者组。确定所确定的患者组,即患有创伤性偏头痛后的特定患者;通过将治疗有效量的药学上安全的肉毒杆菌神经毒素以药学上安全的形式注射给所选择的患者的头部或上颈;施用优选在三叉神经颈系统的部位上进行,从而使得神经毒素能够从远端到中心部位进行轴突运输。并且给药优选包括将适当稀释度的神经毒素肌肉外注射(a)在腱膜筋膜上,或(b)在蝶ala神经节的孔内口服,或(c)至包括孔位的神经的新兴出口点。

著录项

  • 公开/公告号US8420106B1

    专利类型

  • 公开/公告日2013-04-16

    原文格式PDF

  • 申请/专利权人 WILLIAM J. BINDER;

    申请/专利号US201213478828

  • 发明设计人 WILLIAM J. BINDER;

    申请日2012-05-23

  • 分类号A61K39/08;A61P25;C07K14;

  • 国家 US

  • 入库时间 2022-08-21 16:46:13

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