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Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
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机译:利用双回波稳态序列的磁共振方法定量分子扩散
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摘要
Disclosed is a magnetic resonance method for the quantification of molecular diffusion. The method uses a diffusion-weighted (dw) double echo steady state sequence (DESS). In particular, the method allows direct quantification of molecular diffusion from two steady state scans with differing diffusion weighting such as one with diffusion-weighting and preferably one without diffusion weighting. Such a quantification of molecular diffusion allows for rapid and/or quantitative measurements of physiological and/or functional parameters of living tissue. Quantitative measurements are often a prerequisite for pre-clinical and clinical research as well as for clinical trials in drug research performed at different sites. Especially for the early diagnosis of subtle or diffuse pathological changes, quantitative MR promises to have a very significant impact.
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