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Method of reversing carboplatin resistance by inhibition of HGFIN
Method of reversing carboplatin resistance by inhibition of HGFIN
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机译:通过抑制HGFIN逆转卡铂耐药性的方法
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摘要
The present invention discloses the cloning of a new cDNA, HGFIN, from stimulated bone marrow stromal cells that was retrieved with a probe specific for the neurokinin-1 (NK-1) receptor. The novel gene, HGFIN, encodes a protein receptor that is involved in the regulation of hematopoietic proliferation and differentiation. HGFIN is implicated in the treatment of hyperproliferative disorders, particularly bone and breast cancer, because it acts to suppress the proliferating cells.
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