immunogenic protein particle, composition, use of a protein or composition, method for treating a patient susceptible to plasmid infection, host coding DNA sequences, process for producing a particle, and, product

摘要

IMMUNOGENIC PROTEIN PARTICULAR, COMPOSITION, USE OF A PROTEIN OR COMPOSITION, METHOD FOR TREATING A SUSPECTIBLE PATIENT, PLASMA INFECTION DNA SEQUENCES, PRODUCT PROCEDURE, PRODUCT PART The present invention relates to a novel lipoprotein particle, methods for preparing and purifying it, its use in medicine, particularly in the prevention of malarin infections, particle-containing compositions or antibodies to the protein particle such as monoclonal antibodies or polyclonal drugs and their use, particularly in therapy. In particular, it relates to an immunogen protein particle comprising the following monomers: a. a fusion protein protein comprising sequences derived from a P. vivax CS protein and Hepatitis B antigen S (CSV-S) and b. a fusion protein comprising sequences derived from P. falciparum CS proteins and antigen Hepatitis B S (RTS) and o. optionally, antigen S derived from Hepatitis B.