Biossensor to detecu00c7u00e7o of hormu00e2nios goiter and applications in nanomedicine

摘要

Biossensor to detecu00c7u00e7o of hormu00e2nios goiter and applications in nanomedicine. Construction of a biossensor for detection of hormones goiter and synthetic analogues using an electrode containing tracks interdigitadas gold.In this device, both the solid surface on the solid surface of the trails of gold, were previously prepared with silane agents and binary mixture of tiois using the technique of self - organized monolayers (SAMs). On these surfaces prepared was pinned region of human nuclear receptor LBD goiter tr 225 1 for "casting".The detection of these hormones is carried out according to the electrical measurements of impedance and resistance, which may be related to the concentrations of the analytes in a single axis of coordinates, with capacitance or resistance versas concentrau00e7u00e3o.esta methodology allows to obtain A biossensor to hormones such as goiter, T3, T4 and triac, as well as to synthetic ligands, such as GC - 1.